205

615

1,917,639 → 1,918,256

Represses ''[[gene|uvrB]], [[gene|bstG]], [[gene|tagC]], [[gene|recA]]'' genes and itself by binding to the 14 bp palindromic sequence 5'-CGAACNNNNGTTCG-3'. In the presence of single-stranded DNA, [[protein|RecA]] interacts with [[protein|LexA]] causing an autocatalytic cleavage which disrupts the DNA-binding part of [[protein|LexA]], leading to derepression of the SOS regulon and eventually DNA repair. (according to Swiss-Prot)

Represses ''[[protein|uvrB]], [[protein|dinB]], [[protein|dinC]], [[protein|recA]]'' genes and itself by binding to the 14 bp palindromic sequence 5'-CGAACNNNNGTTCG-3'. In the presence of single-stranded DNA, [[protein|RecA]] interacts with [[protein|LexA]] causing an autocatalytic cleavage which disrupts the DNA-binding part of [[protein|LexA]], leading to derepression of the SOS regulon and eventually DNA repair. (according to Swiss-Prot)

[[this]]

[[this]]

dinR

[SW|DNA repair/ recombination], [SW|transcription factors and their control]

''[[protein|lexA]]'' [Pubmed|1657879]

induced upon DNA damage ([[protein|LexA]]) [Pubmed|1657879,8899710,16267290]

autorepression

[[protein|LexA]]: transcription repression [Pubmed|1657879,8899710,16267290]